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Anti-KIF15 Antibody

Rabbit IgG polyclonal antibody for KIF15 detection. Tested with WB, IHC-P, Direct ELISA in Human;Mouse;Rat.

分类:

一抗 - 多克隆抗体

说明书:

A05983-1

1980元/100ug  

human, mouse, rat

WB,IHC-P,Direct ELISA

Polyclonal

现货

选择规格:

总价格:

---元*1

选择数量:

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Product Brief

  • 产品概况

    产品名称Anti-KIF15 Antibody
    产品描述Rabbit IgG polyclonal antibody for KIF15 detection. Tested with WB, IHC-P, Direct ELISA in Human;Mouse;Rat.
    文献引用格式Anti-KIF15 Antibody (Boster Biological Technology, Wuhan, China. Catalog #A05983-1)
    应用范围WB,IHC-P,Direct ELISA
    抗体来源Rabbit
    抗体亚型Rabbit IgG
    推荐配套的二抗和检测试剂Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
    *Blocking peptide 可以联系我们购买。
    免疫原E.coli-derived human KIF15 recombinant protein (Position: M1201-S1388).
    抗体规格100ug/vial

    产品详情

    克隆Polyclonal
    产品形态Lyophilized
    内容Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
    *可以提供无载体抗体。
    浓度Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
    储存条件At -20℃ for one year. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for a longer time. Avoid repeated freezing and thawing.

    指标相关信息 (来源: Uniprot.org)

    小贴士:你可以利用tissue specificity信息来帮助设计阳性和阴性对照。对此有疑问请联系我们技术服务部门。
    基因名KIF15
    基因全名kinesin family member 15
    Uniprot IDKIF15: Q9NS87

    指标背景简介

    Kinesin family member 15 is a protein that in humans is encoded by the KIF15 gene. It is mapped to 3p21.31. This gene encodes a motor protein that is part of the kinesin superfamily. KIF15 maintains half spindle separation by opposing forces generated by other motor proteins. KIF15 co-localizes with microtubules and actin filaments in both dividing cells and in postmitotic neurons. KIF15 (also known as Kinesin-12 and HKLP2) is a motor protein expressed in all cells during mitosis and in postmitotic neurons undergoing axon growth. KIF15 maintains bipolar microtubule spindle apparatus in dividing cells and shares redundant functions with KIF11. KIF15 is thought to promote spindle assembly by cross-linking and sliding along microtubules creating a separation between centrosomes. HeLa cells depleted of KIF11, with reduced microtubule dynamics, are able to form bipolar spindles from acentrosomal asters in a KIF15 dependent manner. Hence, inhibition of KIF15 function will be a vital therapeutic approach in cancer chemotherapy.

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